Xvent-2 expression in regenerating Xenopus tails
نویسندگان
چکیده
منابع مشابه
Requirement for Xvent-1 and Xvent-2 gene function in dorsoventral patterning of Xenopus mesoderm.
Xvent-1 and Xvent-2 are members of a novel homeobox subfamily that have been implicated in dorsoventral patterning in Xenopus mesoderm and are thought to function in BMP signalling. Here we investigate the requirement for Xvent function by employing two dominant-negative strategies. Loss of Xvent function dorsalizes ventral mesoderm, induces secondary embryonic axes and directly neuralizes ecto...
متن کاملExpression of the transcription factor Xvent-2 in Xenopus laevis embryogenesis
Till now the transcription factor Xvent-2 has been studied in Xenopus embryos only by the mRNA testing. We use immunochemical methods for testing of the Xvent-2 protein and gradient-centrifugation methods for estimation of activity of its mRNA. Our results show that the Xvent-2 protein is present in eggs and early embryos. The Xvent-2 mRNA is absent at any of these developmental stages. The maj...
متن کاملFactors guiding regenerating retinotectal fibres in the frog Xenopus laevis.
I have examined the pathways of retinotectal fibres regenerating back to the contralateral tectum, and also to innervated and 'virgin' ipsilateral tecta in postmetamorphic Xenopus. The fibres were visualized by HRP labelling of either the whole optic nerve, or a selected quadrant of the retina. Most fibres grow into either the ipsilateral or contralateral optic tract, although a small proportio...
متن کاملThe diencephalic course of regenerating retinotectal fibres in Xenopus tadpoles.
The normal retinotectal path in the diencephalon of Xenopus tadpoles is widely distributed in the form of a wedge of fibres extending from the central grey to the outer margin of the diencephalon. Regenerating optic nerve fibres were shown, by silver-staining and proline autoradiography, to follow an abnormal path up the extreme lateral edge of the diencephalon. Study of tadpoles at various sta...
متن کاملDevelopmental expression of Shisa-2 in Xenopus laevis.
Shisa is an antagonist of Wnt and FGF signaling, that functions cell autonomously in the endoplasmic reticulum (ER) to inhibit the post-translational maturation of Wnt and FGF receptors. In this paper we report the isolation of a second Xenopus shisa gene (Xshisa-2). Xenopus Shisa-2 shows 30.7% identity to Xshisa. RT-PCR analysis indicated that Xshisa-2 mRNA is present throughout early developm...
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ژورنال
عنوان ژورنال: Stem Cell Investigation
سال: 2020
ISSN: 2313-0792
DOI: 10.21037/sci-2019-044